The problem
Protein function and stress-response annotation require evidence-rich workflows that can combine biological knowledge with high-dimensional sequence features.
The approach
Compare engineered amino-acid features with ESM2 protein embeddings across multiple classifiers, cross-validation strategies and calibrated thresholds.
Evidence and outputs
- Model comparison
- Feature pipeline
- Interactive prototype
- Evaluation notes
Tools and methods
Evidence standard
This profile deliberately separates current status from ambition. Links appear only when a repository, demo or public output has been supplied.